Cocaine

-- { Coke, Snow, Charlie, Crack Rock } --

Cocaine is a powerful stimulant drug, derived from the coca plant, predominantly used for recreational purposes. It affects the central nervous system, heightening alertness, increasing energy, and creating feelings of euphoria. Long-term usage can lead to serious heart health issues.

Introduction Effects Dosage Trip Reports Interactions Reagent Testing Harm Reduction Risks The Law References

What is Cocaine?

Cocaine is a powerful and highly addictive stimulant drug that is derived from the leaves of the coca plant native to South America. It is typically found in a white, crystalline powder form, but can also be processed into a rock crystal or "crack" cocaine. It is primarily used recreationally for its euphoric and energizing effects. However, due to its highly addictive nature and significant health risks, it is classified as a Schedule II drug in the United States, indicating a high potential for abuse.

How it Works

From a pharmacological perspective, cocaine works by inhibiting the reuptake of neurotransmitters—primarily dopamine, but also norepinephrine and serotonin—in the brain. This leads to an excess of these neurotransmitters in the brain's reward circuit, thereby amplifying their effects. Dopamine, in particular, is associated with pleasure and movement, so its heightened presence contributes to cocaine's stimulant effects. It's worth noting that the changes cocaine makes to the brain's reward system can lead to addiction and physical dependence.

History

The history of cocaine extends back thousands of years, with the coca plant used for its stimulant effects by indigenous cultures in South America. It wasn't until the mid-19th century, however, that cocaine was first isolated from coca leaves. The drug rapidly gained popularity in Western medicine and was even included in products like tonics and the original formulation of Coca-Cola. However, by the early 20th century, the addictive potential and negative health effects of cocaine were becoming increasingly clear, leading to its criminalization in many jurisdictions.